The difference between liver and kidney

I wrote this article the difference between liver and kidney to help people know more about the two organs, especially the functions and the structure of the organs. At the end of the blog, I added some of the relevant information to help people learn more about the two organs.

The difference between liver and kidney

Main differences-liver and kidneys

Try to Understand:

The liver and kidneys are two important organs in an animal’s body. The liver is the second largest internal organ of the body. It is on the right side of the belly. The kidneys are two bean-shaped organs located under the thorax on both sides of the spine. 

The main difference between the liver and the kidneys The liver is involved in the synthesis of proteins, glycogen, triglycerides, cholesterol and bile, but the kidneys remove waste products and excess water from the body. .. The liver is also involved in the breakdown of food, the purification of blood, and the storage of energy. 

The kidneys regulate the body’s salt, potassium, and acid content. It also serves as an endocrine organ by producing hormones.

Target field

What is the Liver
      -Definition, Anatomy, Physiology
What is the Kidney
      -Definition, Anatomy, Physiology
What are the similarities between the liver and the kidney?
      –Overview of common functions
4. What is the difference between the liver and kidneys
      -Comparison of the main differences

Keywords: digestion, excretion, homeostasis, kidney, liver, lobule, metabolism, nephron, storage

What is the liver?

The liver is a large lobular glandular organ in the abdomen of vertebrates. It performs functions related to digestion, metabolism, storage and body exemption. It is located just below the diaphragm, and most of the liver mass is localized to the right side of the abdomen. 

The liver is made of soft pinkish-brown tissue and is encapsulated by connective tissue capsules that are further strengthened by the peritoneum. The four leaves of the liver are left, right, caudate, and quadrate. The largest robes are the left and right robes. They are separated by the phantom ligaments. The anatomy of the liver is shown in Figure 1.

Figure 1: Liver

The microstructure of the liver is composed of about 100,000 hexagonal functional units called lobules. There is a central vein in the center of each lobe, which connects to the hepatic vein. 

Each lobe is also surrounded by 6 hepatic arteries, 6 hepatic portal veins, and 6 bile ducts. Capillary-like tubes extend from the hepatic artery and portal vein to the central vein. These capillary tubes are called sine waves. 

Sine soid is surrounded by hepatocytes and Kupffer cells. The microscopic anatomy of the liver is shown in Figure 2.

Figure 2: Microscopic anatomy of the liver

Hepatocytes are the majority of hepatocytes. They perform liver functions such as digestion, metabolism, storage and bile production. Kupffer cells capture old and worn red blood cells and break them down.

What is a kidney?

The kidney means each pair of organs in the abdominal cavity of mammals, birds, and reptiles that excrete urine. Two kidneys can be seen along the posterior muscle wall of the abdominal cavity. They are behind the peritoneum. The kidney capsule, renal cortex, and renal medulla are the three zones of the kidney. 

The renal medulla is composed of approximately seven kidney pyramids. Their base faces the renal cortex and the apex faces the center of the kidney. Each vertex connects to a secondary y. Each y is open to the renal pelvis. The anatomy of the kidney is shown in Figure 3 .

What is a kidney?

Figure 3: Kidney

Nephrons are the functional unit of the kidney and are responsible for the filtration of blood. One kidney can contain approximately 1 million kidneys. The renal corpuscle and renal tubules are the two components of the nephron. The kidney body is composed of Bowman’s capsule and glomerular capillaries. 

Bowman capsules are made up of a special type of epithelial cells called podocytes. Proximal circumflex tubules, looped Henle, distal circumflex tubules, and collecting ducts are nephron capillaries. The anatomy of the nephron is shown in Figure 4 .

Figure 4 Nephron

Figure 4 Nephron

Filtration, reabsorption, and secretion are the three functions of nephrons. The final product of nephrons is called urine and contains urea. Water homeostasis, acid / base homeostasis, electrolyte homeostasis, and blood pressure homeostasis are the major regulatory functions of the kidney. Calcitriol and erythropoietin are two hormones produced by the kidneys. Calcitriol enhances calcium absorption in the intestinal tract. Erythropoietin stimulates the bone marrow to make red blood cells.

Similarities between liver and kidney

  • Both the liver and kidneys are important organs of the animal’s body.
  • Both the liver and kidneys are involved in the excretion of substances from the body.

Difference between liver and kidney


Liver: The liver is a large lobular glandular organ in the abdomen of vertebrates that is involved in metabolism.

Kidney: The kidney means each pair of organs in the abdominal cavity of mammals, birds, and reptiles that excrete urine.


Liver: The liver is located just below the diaphragm, in the upper right part of the abdominal cavity.

Kidneys: The kidneys are below the ribs and on both sides of the spine.


Liver: The liver is attached to the peritoneum.

Kidney: The kidney is behind the peritoneum.


Liver: The liver is the second largest internal organ in the body and at the same time the largest gland.

Kidney: The kidney is a very complex organ, made up of thousands of nephrons.


Liver: The liver belongs to the body’s digestive system.

Kidney: The kidney belongs to the body’s urinary system.


Liver: There is only one liver in the body.

kidney: There are two kidneys in the body.


Liver: The main function of the liver is the metabolism of carbohydrates, lipids and proteins.

kidney: The main function of the kidney is the elimination of waste products and the regulation of osmotic pressure.

Other features

Liver: The production of bile and clotting factors is another function of the liver.

kidney: Hormone secretion, blood pressure regulation, and maintenance of pH in the body are other functions of the kidney.


Liver: The liver excretes metabolic waste as a bile pigment from hemoglobin degradation.

kidney: The kidneys excrete ammonia, urea, uric acid, urochrome, water, and certain inorganic irons.


Liver: The liver stores glycogen, fat, ions, and vitamins.

kidney: The kidney does not store any substances.


The liver and kidneys are two important organs of the animal’s body. The liver is mainly involved in the metabolism of carbohydrates, proteins and lipids. It also stores nutrients. The kidney is the main excretory organ of the body. The main difference between the liver and kidneys is the function of each organ in the body.


1. “Liver”.

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